 The
original Sore No More Warm
Therapy
crème has 0.03% extract of “Capsacini” which is
derived from a plant in the Chilli Family. Capsaicin
selectively binds to a protein known as TRPV1 that
resides on the membranes of pain and heat sensing
neurons. TRPV1 is a heat activated calcium channel,
which opens between 37 and 45 °C When capsaicin binds to
TRPV1, it causes the channel to open below 37°C the
normal human body temperature, which is why capsaicin is
linked to the sensation of heat. Capsaicin is used in
topical ointments to relieve the pain of peripheral
neuropathy. In concentrations of between 0.025% and
0.075%. It can be used as a cream for the temporary
relief of minor aches and pains of muscles and joints
associated with arthritis, simple backache, strains and
sprains. Capsacini is one of the very few natural pain
relievers recommended by the Arthritis council.
A PDF
clinical report can be downloaded from http://www.arc.org.uk/arthinfo/documents/6300.pdf
The New COOL Sore No More
does not contain any alcohol and derives it cooling and
analgesic properties from Menthol (U.S.P 6.0%).
Menthol's ability to chemically trigger the
cold-sensitive TPRN8 receptors in the skin is
responsible for the well known cooling sensation that it
provokes when applied. In this sense it is similar to
capsaicin the chemical responsible for the spiciness of
hot peppers (which stimulates heat sensors, also without
causing an actual change in temperature).
Both versions of Sore No More are 100% natural, and are
therefore suitable for use by patients that are
vegetarian/vegan and those who have religious or ethical
dispositions to alcohol.
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